The everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of the frenetic cardiac unit of Holby City General Hospital.

Petra professionally works as a thief abroad to finance the studies of her younger sister Franziska in Germany. When she returns, she realizes that her sister has a secret, too.

莎拉在藝廊賣力工作，卻因病昏倒，不小心摔壞名畫而遭解雇。更慘的是，醫生竟宣布她懷孕近半年的消息，她卻渾然不自知。這個人生從來都是我行我素的女孩，於是決定小孩一生下來就送人。她照樣讀書、玩樂、談戀愛，但即使再怎麼叛逆反骨，…

拉斯是个小寿司店的老板，生意惨淡，靠借贷维持生计。母亲的突然去世使他平淡的生活涟漪不断......

一位驻日本的美国记者被派去采访一位在山间实验室进行奇异实验的怪诞的日本科学家。当医生意识到不幸的记者是他下一个实验的完美对象时，他给这个不幸的人注射药物，然后给他注射血清，逐渐把他变成一个可怕的、两头的怪物。